It is not clear whether vardenafil is the actual cause of vision loss. Staxyn (vardenafil disintegrating tablets) may contain phenylalanine.
What happens if I overdose?
The frequent vardenafil-specific side-effect is nausea; the infrequent side effects are abdominal pain, back pain, photosensitivity, abnormal vision, eye pain, facial edema, hypotension, palpitation, tachycardia, arthralgia, myalgia, rash, itch, and priapism. One possibly serious, but rare, side effect with vardenafil is heart attack. Also, in rare cases, vardenafil use may cause priapism, a very painful emergency condition that can cause impotence if left untreated. In October 2007, the U.S. Food and Drug Administration (FDA) announced that a warning about possible deafness (sudden hearing loss) would be added to the drug labels of vardenafil, and other PDE5 inhibitors.
Pharmacological Class
Vardenafil should not be used by people taking nitrate medications, because combining them with vardenafil might provoke potentially life-threatening hypotension (low blood pressure). Further, vardenafil causes lengthening of the QT interval. Therefore, it should not be taken by people taking other medications that affect the QT interval (such as amiodarone). Vardenafil was co-marketed by Bayer Pharmaceuticals, GlaxoSmithKline, and Schering-Plough under the brand name Levitra. As of 2005, the co-promotion rights of GSK on Levitra have been returned to Bayer in many markets outside the US. Vardenafil is not approved for use in women, and the effects of vardenafil during pregnancy or in breastfeeding women are unknown.
| Product | Dosage | Quantity + Bonus | Price | |
|---|---|---|---|---|
| Kamagra Oral Jelly | 100 mg | 63 + 7 Sachets | 224.18€ 213.50€ | |
| Viagra Super Active | 100mg | 180 + 20 Pills | 280.97€ 267.59€ | |
| Cialis Original | 20mg | 34 + 2 Pills | 183.99€ 175.23€ | |
| Viagra Generic | 150mg | 180 + 10 Pills | 236.46€ 225.20€ | |
| Viagra Super Active | 100mg | 20 + 4 Pills | 48.05€ 45.76€ | |
| Levitra Generic | 60mg | 20 Pills | 81.30€ 77.43€ | |
| Kamagra | 100mg | 360 + 6 Pills | 839.95€ 799.95€ | |
| Cialis Generic | 60mg | 90 + 6 Pills | 196.67€ 187.30€ | |
| Kamagra Oral Jelly | 100 mg | 220 + 18 Sachets | 662.24€ 630.70€ | |
| Kamagra Oral Jelly | 100mg | 220 + 18 Sachets | 662.24€ 630.70€ |
Staxyn (vardenafil disintegrating tablets) should not be used in place of Levitra (vardenafil regular tablets). Avoid medication errors by using only the form and strength your doctor prescribes.
Cited by (73)
"Unapproved Pharmaceutical Ingredients Included in Dietary Supplements Associated With US Food and Drug Administration Warnings". Generic name: vardenafil [ var-DEN-a-fil ] Brand names: Levitra, Staxyn Dosage forms: oral tablet (10 mg; 2.5 mg; 20 mg; 5 mg), oral tablet, disintegrating (10 mg) Drug class: Impotence medications Vardenafil is used in adult men to treat erectile dysfunction (impotence). Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop using vardenafil and get emergency medical help if you have: heart attack symptoms--chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating; heart attack symptoms--chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating; vision changes or sudden vision loss; or vision changes or sudden vision loss; or erection is painful or lasts longer than 4 hours (prolonged erection can damage the penis). erection is painful or lasts longer than 4 hours (prolonged erection can damage the penis).
Optum Perks
Stop using vardenafil and call your doctor at once if you have: ringing in your ears, or sudden hearing loss; ringing in your ears, or sudden hearing loss; swelling in your hands, ankles, or feet; swelling in your hands, ankles, or feet; a light-headed feeling, like you might pass out; or a light-headed feeling, like you might pass out; or Common side effects of vardenafil may include: flushing (sudden warmth, redness, or tingly feeling); flushing (sudden warmth, redness, or tingly feeling); This is not a complete list of side effects and others may occur. Some medicines can cause unwanted or dangerous effects when used with vardenafil. Tell your doctor about all your other medicines, especially riociguat (Adempas). Do not take vardenafil if you are also using a nitrate drug for chest pain or heart problems, including nitroglycerin, isosorbide dinitrate, isosorbide mononitrate, and some recreational drugs such as "poppers". Taking vardenafil with a nitrate medicine can cause a sudden and serious decrease in blood pressure. Follow all directions on your prescription label and read all medication guides or instruction sheets. Vardenafil can be taken with or without food. Remove an orally disintegrating (Staxyn) tablet from the package only when you are ready to use the medicine.
What is premenopause?
Call your doctor or seek emergency medical attention if your erection is painful or lasts longer than 4 hours. A prolonged erection (priapism) can damage the penis. Stop using vardenafil and get emergency medical help if you have sudden vision loss. You should not use vardenafil if you are allergic to it, or if you take other medicines to treat pulmonary arterial hypertension, such as riociguat (Adempas). Do not take vardenafil if you are also using a nitrate drug for chest pain or heart problems, including nitroglycerin, isosorbide dinitrate, and isosorbide mononitrate.
3.2 Dosing
Nitrates are also found in some recreational drugs such as vigora 200 mg amyl nitrate or nitrite ("poppers"). Tell your doctor if you have ever had: a heart attack, stroke, or congestive heart failure; a heart attack, stroke, or congestive heart failure; long QT syndrome (in you or a family member); long QT syndrome (in you or a family member); a blood cell disorder such as sickle cell anemia, multiple myeloma, or leukemia; a blood cell disorder such as sickle cell anemia, multiple myeloma, or leukemia; an eye disorder such as retinitis pills for womens libido pigmentosa (an inherited condition of the eye); an eye disorder such as retinitis pigmentosa (an inherited condition of the eye); a physical deformity of the penis (such as Peyronie's disease); a physical deformity of the penis (such as Peyronie's disease); if you have been told you should not have sexual intercourse for health reasons; or if you have been told you should not have sexual intercourse for health reasons; or liver disease, kidney disease (or if you are on dialysis). liver disease, kidney disease (or if you are on dialysis). Vardenafil can decrease blood flow to the optic nerve of the eye, causing sudden vision loss. This has occurred in a small number of people, most of whom also had heart disease, diabetes, high blood pressure, high cholesterol, or certain pre-existing eye problems, and in those who smoked or were over 50 years old. Place the tablet in your mouth and allow it to dissolve without chewing. Swallow several times as the tablet dissolves.
Overdose/Missed Dose
Archived from the original on July 9, 2009. "Pharmacology and drug interaction effects of the phosphodiesterase 5 inhibitors: focus on alpha-blocker interactions". "The QT Interval and Selection of Alpha-Blockers for Benign Prostatic Hyperplasia". ^ "New erectile dysfunction treatment Staxyn approved in the U.S. - Pharmaceutical Processing".
Related treatment guides
Archived from the original on April 6, 2012. ^ "Staxyn - New Innovation in Erectile Dysfunction Helps Younger Men Rise to the Occasion". U.S. Food and Drug Administration (FDA). ^ Tucker J, Fischer T, Upjohn L, Mazzera D, Kumar M (October 2018). Vardenafil is taken only when needed, about 60 minutes before sexual activity. The medicine can help achieve an erection when sexual stimulation occurs. An erection will not occur just by taking a pill. If you receive medical care for heart problems, tell your caregivers when you last took vardenafil.
- 20 mg vardenafil is used to treat erectile dysfunction in men.
- It enhances blood flow to the penis during sexual activity.
- Vardenafil should be taken about 30-60 minutes before sex.
- The usual dose varies; 20 mg is a common prescribed amount.
This medicine does not prevent the spread of sexually transmitted diseases such as human immunodeficiency virus (HIV). Store at room temperature away from moisture and heat. -Initial dose: 10 mg orally once a day, as needed, approximately 60 minutes before sexual activity.
| Region | Approximate Cost | Notes |
|---|---|---|
| North America | $10 - $15 | Generic versions available |
| Europe | €8 - €12 | Brand and pharmacy differences |
| Asia | $2 - $8 | Widely available, varies by country |
| Online Pharmacies | $3 - $10 | Verify authenticity |
Increase to 20 mg or decrease to 5 mg based on efficacy and tolerability.-Maximum dose: 20 mg once a dayPatients on stable alpha blocker therapy:-Initial dose: 5 mg orally once a dayComments:-Sexual stimulation is required for a response to treatment.-A time interval between dosing should be considered when administering this drug concomitantly with alpha-blockers.-Patients taking alpha-blockers should not initiate vardenafil therapy with the orally disintegrating tablet.Use: Erectile dysfunction 65 years or older:-Initial dose: 5 mg orally once a day, as needed, approximately 60 minutes before sexual activityComments: Sexual stimulation is required for a response to treatment.Use: Erectile dysfunction Since vardenafil is used as needed, you are not likely to be on a dosing schedule.
Proper Use
Thus, because of European Union trade rules, parallel imports might result in Vivanza sold next to Levitra in the EU. An orally disintegrating form, marketed as Staxyn and Levitra Soft, has been gaining approvals in countries such as the United States[11] and Canada. The US Food and Drug Administration (FDA) has found vardenafil and other synthetic PDE5 inhibitors in numerous products marketed as "herbal" supplements or "all natural" products for male enhancement. ^ a b c d "Levitra (vardenafil hydrochloride) tablets, for oral use Initial U.S. Approval: 2003".
2.1 Study design
^ "Levitra (Vardenafil) is A Drug Used to Treat Erectile Problems in Men" (in German). "Potency, selectivity, and consequences of nonselectivity of PDE inhibition". "Effects of vardenafil administration on intravaginal ejaculatory latency time in men with lifelong premature ejaculation". "Counseling Patients About Sexual Issues: Drug-Induced Priapism". ^ "FDA Announces Revisions to Labels for Cialis, Levitra and Viagra". Allow 24 hours to pass between doses.
| Country | Status | Remarks |
|---|---|---|
| United States | Prescription-only | FDA-approved for ED |
| United Kingdom | Prescription-only | MHRA regulation |
| India | Over-the-counter / Prescription | Varies by state |
| Australia | Prescription-only | TGA regulation |
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Grapefruit and Seville oranges may interact with vardenafil and cause side effects. Avoid consuming grapefruit products and orange marmalades. Drinking alcohol can increase certain side effects of vardenafil.
| Drug | Onset of Action | Duration | Efficacy Rating | Comments |
|---|---|---|---|---|
| Vardenafil | 30-60 min | Up to 5 hrs | High | Less affected by food intake |
| Sildenafil | 30-60 min | Up to 4 hrs | Moderate to High | Commonly used, less selective |
| Tadalafil | 30 min - 2 hrs | Up to 36 hrs | Very High | Longer duration of effect |
| Avanafil | 15-30 min | Up to 6 hrs | High | Fastest onset |
Do not use any other medicine to treat impotence unless your doctor tells you to. Do not use vardenafil with similar medications such as avanafil (Stendra), sildenafil (Viagra), or tadalafil (Cialis). Tell your doctor about all other medications you use for erectile dysfunction. This list is not complete and many other drugs may affect vardenafil. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
- 20 mg vardenafil is effective in improving erectile function in most men.
- Be aware of potential allergic reactions, such as rash or swelling.
- The medication can interact with certain antibiotics and antifungals.
- Regular check-ups are recommended during prolonged use of vardenafil.